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br Conclusions br Conflict of
2024-11-26
Conclusions Conflict of interest Introduction Plants often encounter a series of abiotic stresses during the growth process, including high salinity, extreme temperatures and drought (Knight and Knight, 2001). Plants can adapt through ionic and osmotic homeostasis or osmotic adjustment, con
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PKA signalling in the http www apexbt
2024-11-26
PKA signalling in the nucleus was thought to be due to the translocation of the catalytic subunit upon activation from the kainic acid to the nucleus via diffusion [72]. However, a new understanding has emerged, as both the regulatory and catalytic subunits have been identified in the nucleus and f
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br Introduction Clinical manifestations of Alzheimer s disea
2024-11-26
Introduction Clinical manifestations of Alzheimer's disease (AD) are mainly characterized by progressive intellectual deterioration, memory impairment, cognitive impairment, and psychiatric symptoms. The pathogenesis of AD remains unclear, mainly containing genetic factors, neurotransmitter disor
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The extent to which GPCR oligomerization is a
2024-11-26
The extent to which GPCR oligomerization is a regulated process still remains unclear. Reported effects of ligands on both GPCR homo- and heteromers are highly variable and depend on GPCR subtypes and the specific ligand used. According to our data, chronic treatment of mice with both paroxetine or
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Similar to V the temporal neocortex
2024-11-26
Similar to V1, the temporal neocortex of mammals, including the primary auditory cortex (A1), is densely innervated by 5-HT fibers originating mainly in the dorsal raphe nucleus (Campbell et al., 1987, Harding and Paxinos, 2004, Törk, 1990), and the major L-817,818 receptor of 5-HTRs are expressed
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Acl converts cytosolic citrate CoA and
2024-11-26
Acl converts cytosolic citrate, CoA and ATP into acetyl-CoA, ADP+Pi and oxaloacetate (Fig. 1). This cytosolic enzyme is present in few Prokaryotes and in all Eukaryotes, but not in non-oleaginous yeasts [14]. Thus, this enzyme was presumed to be essential for FA synthesis [1], [13], [15]. In most mi
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The mitogen activated protein kinase MAPK plays an
2024-11-25
The mitogen-activated protein kinase (MAPK) plays an important role in a variety of cell processes by controlling transcriptional or translational regulation [14]. There are three major MAPK family members that have been well characterized: extracellular signal-regulated kinase (ERK), c-Jun N-termin
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We initially established using fMRI that auditory processing
2024-11-25
We initially established using fMRI that auditory processing by the caudomedial nidopallium (NCM) of male European starlings (Sturnus vulgaris) of species-specific aspects of songs (whistles and warblings i.e. high-pitched trills coming from the end of the warbling that are found in the repertoire o
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br Acknowledgment Supported in part by NIH
2024-11-25
Acknowledgment Supported in part by NIH1R21EB012707 (Biegon, Anat PI). Introduction Estrogens exert pleiotropic effects on a variety of morphological, physiological and behavioral responses in all vertebrate classes ranging from fishes to mammals. Effects of estrogens in the protease inhibito
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The putative residue apelin proprotein proapelin or apelin i
2024-11-25
The putative 55-residue apelin proprotein (proapelin or apelin-55) is processed from a 77-residue preproprotein through removal of a 22-residue signal peptide (Table 1). Apelin-55 is further processed into bioactive isoforms of 36, 17, or 13 residues, likely through protease-mediated mechanisms. To
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br Introduction The term antioxidant derives from the preven
2024-11-25
Introduction The term antioxidant derives from the prevention of the oxygen consumption. In the late of 19th centuries, antioxidants were generally used in industrial processes such as against to metal corrosion, vulcanization of rubber. Later on, the use of antioxidants to prevent the rancidity
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faah inhibitor Bran is a byproduct of flour milling
2024-11-25
Bran is a byproduct of flour milling, typically utilized as a valuable component of animal feeds. Because of its attractive technological and health-promoting properties, it faah inhibitor has also been increasingly used in food manufacturing as a source of dietary fiber. Indeed, with the growing i
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On the other hand oxygen concentration in tumor
2024-11-25
On the other hand, oxygen concentration in tumor tissue also depends on its consumption rate by tumor cells, which decrease will also lead to alleviation of hypoxia. This fact is not taken into account in the majority of studies on the topic, although it is well-known that antiangiogenic therapy doe
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br Androgen interference with the action
2024-11-25
Androgen interference with the action of arachidonic Q-VD(OMe)-OPh receptor metabolites’ actions; the other side of the coin Arachidonic acid, being a polyunsaturated fatty acid present in the phospholipids of the membrane of cells, is highly abundant within the organism. It is mainly involved i
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br Results br Discussion Using
2024-11-25
Results Discussion Using primarily an electrophysiological analysis of dysbindin-deficient hippocampal neurons in cultures and slices, we have uncovered a previously unreported role for dysbindin in enhancing CA3–CA1 AMPAR-mediated transmission. An earlier study, however, has reported a reduct
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